Involuntary weight loss is a marker of potential problems, and weight restoration is a potential solution. However, the real key diagnostic information is the status of body composition (Table 3 ). Since normal body composition for the individual of concern is not known prior to the insult, a host of normalized tables and equations, with an assumed normal value, are used. Therefore, the actual alteration of body composition caused by an insult or poor nutrition (or usually both) is not known. The complications, for example, the weakness seen in the patient, as well as the presence of a catabolic state that will lead to LBM loss, are often the best clinical markers. Of the available methods (Table 3 ), skin-fold thickness and bioelective impendence are valuable if taken sequentially over time, but some form of baseline is needed; on the other hand, nitrogen balance provides direct information as to whether the patient was catabolic or anabolic on the measurement day, and how catabolic. 22 28
The use of anabolic steroids will suppress natural testosterone. The rate of suppression is dependent on the steroid in question, but in the case of Oxymetholone it is enough to warrant the use of exogenous testosterone. This will actually hold true with most anabolic steroids. Those who supplement with Anadrol and forgo exogenous testosterone therapy will fall into a low testosterone condition. Not only is this a condition that comes with numerous bothersome symptoms, it is an extremely unhealthy state. The form of testosterone you choose when using Anadrol is of no consequence, however, you should ensure you are applying enough to provide what the body needs.
Once the use of Anadrol and all anabolic steroids has come to an end and all the exogenous hormones have cleared your system natural testosterone production will begin again. This is assuming there was no prior existing low level state. It also assumes no damage was done to the HPTA during supplementation due to improper practices. While natural testosterone production will begin again on its own, it will not be fast. It is generally recommended that the individual begin a Post Cycle Therapy (PCT) treatment plan following anabolic steroid use . This will encourage natural testosterone production and speed the healing process up. It will not automatically return you to your previous natural high level on its own; that will take some time. However, it will ensure you have enough testosterone in your body to function properly while your levels continue to naturally rise.
This drug was first produced in 1964 by a company called Searle. It was designed to be a safe and mind anabolic steroid and in low doses was well tolerated by women and children. Oxandrolone is a Class I anabolic, mildly androgenic steroid, which makes it safe to use in many cases. This drug has been used for anything from, burn victims to treatment of osteoporosis as it provides calcium to the body which will aid in bone regeneration. However in 1989 this drug was discontinued by Searle Laboratories partly due to the illegal use among bodybuilders. Around 6 years later Bio-Technology General Corp negotiated a deal with Searle where they would continue to manufacture the drug Anavar and supply it to BTG. This is when a press release went out stating its effects on involuntary weight loss and focused itself on HIV/AID’s wasting indications which were approved by the FDA where they were able to dictate the price by it being granted Orphan Drug status by the Food and Drug Administration.