Research has shown that most colorectal cancers develop in colorectal polyps. Therefore, removing benign (but precancerous) colorectal polyps can prevent colorectal cancer. Precancerous colorectal polyps are most commonly called adenomatous polyps. They develop when chromosomal damage occurs in cells of the inner lining of the colon. The damage produces abnormal cells, but the cells have not yet developed the ability to spread, the hallmark of cancer. Instead, the growing tissue remains localized within the polyp. When chromosomal damage increases further within the polyp, cell growth becomes uncontrolled, and the cells begin to spread, that is, they become cancer. Thus, colon polyps which are initially benign acquire additional chromosome damage to become cancerous.
Pretty severe means you don’t respond to the treatment. I didn’t. Most women respond to the hormone supplements and at least have a monthly cycle. I haven’t had one since college, even with pills. I get damn tired of having to prove what I ate, how I exercised and how I live just to get medical professionals to treat me with anything resembling respect. I mentioned a surgeon’s screw up: in a few years, I’ll need an organ transplant thanks to that doctor. Of course, that assumes I can get one: the first doctor I saw at the nearest regional “center of excellence”