Users on an oral steroid cycle may experience a sudden increase in body weight and muscular development, insomnia, irritability, aggressive combative behavior, puffy face, severe acne, bad breath, a yellowing of the eyes and skin, premature hair loss, hyperactivity, and exaggerated mood swings that include uncontrollable outbursts of anger. Males may also experience testicular shrinkage and can develop female breast tissue on the pectoral muscles. Females may also experience a deeper voice and decreased breast size. Continued use can result in life-threatening situations involving the liver, cardiovascular system, and brain.
Oxandrolone is most certainly a hepatotoxic steroid. It does not carry the strongest level of hepatotoxicity among anabolic steroids, but it is stronger than most. This is due to it being a C17-aa anabolic steroid. All C17-aa steroids are hepatic, but the level of toxicity varies greatly between them. Due to this steroid’s strong hepatotoxicity, this is why total use must be limited (see administration section).
Due to use, those who supplement with Anadrol will find their liver enzyme values increase. An increase in values is not a sign of damage but rather a sign of stress that can lead to damage if responsible practices are not followed and the stress is allowed to remain. Proper dosing and duration of use protocols are imperative when it comes to this steroid. Further, it is important the individual avoids excess alcohol consumption when supplementing with this steroid due to the liver stress such consumption will cause. In fact, most will find avoiding all alcohol to be best during use. If this is a problem and you are supplementing for the purpose of performance enhancement remember there is nothing on earth that is as anti-performance as alcohol. Those who supplement are also encouraged to limit their use of Over the Counter (OTC) medications. Many OTC medications carry strong hepatic natures, and the added stress can be extensive when coupled with Anadrol. Use should be limited to when only absolutely needed. If these rules can be followed, once use is discontinued liver enzyme values will return to normal and no damage will be done. As a final note, Anadrol should not be used if the liver is unhealthy.
Oxymetholone (also known as anapolon or anadrol) is a very drastic synthetic steroid, 17-alpha-alkylated modification of dihydrotestosterone. It was developed for the treatment of osteoporosis and anaemia, as well as to stimulate muscle gain in malnourished and debilitated patients. Oxymetholone has been approved by the American Food and Drug Administration (FDA) for use in humans. Later there where created non-steroidal drugs that effectively could treat anaemia and osteoporosis; because of this anapolon lost his popularity and by 1993 Syntex decided to cease the production of the drug, as well as other manufacturers did.